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HPLC Columns

Columns used for separation of biomolecules and organic or inorganic analytes; includes normal phase, reversed phase, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
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16 – 30 of 30,878 results
17

Thermo Scientific™ ProPac™ 3R SAX 3 μm HPLC Columns

Get the performance you need with ProPac™ 3R SAX HPLC columns. Suitable for charge variant separations and recommended for therapeutic proteins, mAbs, ADCs, and AAVs.

Pore Size Nonporous
Particle Size 3 μm
Stationary Phase Proprietary
Temperature Ambient to 60°C
Phase Strong Anion Exchange
Packing Material Monodisperse Polymer Resin
Column Type Ion Exchange
pH 2 to 12
Technique Bio-LC
Max. Pressure 4500 psi (310 bar)
Product Line ProPac
Column Format Analytical Column
18

Thermo Scientific™ Hypersil GOLD™ PEI HILIC HPLC Columns
GSA_VA

Retain highly polar and hydrophilic analytes, which are difficult to analyze with conventional C18 columns, using Hypersil GOLD PEI HILIC LC Columns.

Pore Size 175 Å
Carbon Load 6%
Stationary Phase PEI HILIC
Temperature 60°C
Phase HILIC
Endcapped No
pH 2 to 8
Surface Area 220 m²/g
19

Thermo Scientific™ ProPac™ 3R SCX 3 μm HPLC Columns

Get the performance you need with ProPac™ 3R SCX HPLC columns. Suitable for charge variant separations and recommended for therapeutic proteins, mAbs, ADCs, and biosimilar proteins.

Pore Size Nonporous
Particle Size 3 μm
Stationary Phase Proprietary
Temperature Ambient to 60°C
Phase Strong Cation Exchange
Packing Material Monodisperse Polymer Resin
Column Type Ion Exchange
Mobile Phase Compatibility Recommended for use with CX-1 pH buffers
pH 2 to 12
Technique Bio-LC
Max. Pressure 4500 psi (310 bar)
Product Line ProPac
Column Format Analytical Column
20
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Thermo Scientific™ Shodex™ SEC/GPC Phase Mixed Mode HPLC Column, 3 μm, 4.6 mm x 300 mm
GSA_VA

Column Format: Semi-Micro Column; Pore Size: 800 Å; Column Phase: Size Exclusion and Gel-Permeation

21
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Thermo Scientific™ Acclaim™ Mixed Mode WCX-1 HPLC Columns
GSA_VA GREENER_CHOICE

Separate cationic molecules with powerful adjustable selectivity control using this mixed-mode reversed-phase and weak cation-exchange LC column.

EDGE
Pore Size 120 Å
Stationary Phase Hydrophobic Alkyl Chain with a Carboxyl Terminus
Temperature 50°C
Phase Reversed Phase, Ion Exchange, Ion Exclusion, HILIC
Endcapped Proprietary
Column Type Mixed Mode
Green Features FSC
Surface Area 300 m²/g
Product Line Acclaim
USP Type L85
22

Thermo Scientific™ DNAPac™ RP Columns
GREENER_CHOICE

Get high resolution LC and LC-MS separation of oligonucleotides, including double-stranded (ds) DNA/RNA fragments, using these DNAPac reversed phase columns.

EDGE
23

Thermo Scientific™ Accucore™ RP-MS HPLC Columns

Obtain an excellent combination of speed and quality of separation using these solid core columns that are optimized for LC-MS and UHPLC-MS methods.

EDGE
Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 7%
Phase Reversed Phase
Endcapped Yes
pH 2 to 9
Surface Area 130 m²/g
Particle Shape Solid Core
24

Thermo Scientific™ Accucore™ PFP HPLC Columns

Use these solid core particle columns to analyze difficult-to-resolve mixtures including DOA and pharmaceuticals.

EDGE
Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 5%
Stationary Phase PFP
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Packing Material Ultrapure Silica
pH 2 to 8
Surface Area 130 m²/g
Max. Pressure 14500 psi (1000 bar)
Product Line Accucore
USP Type L43
25

Thermo Scientific™ NativePac OBE-1 SEC Column for Online Sample Preparation

Perform Native-MS analysis of biomacromolecules with the NativePac OBE-1 SEC Column designed for rapid exchange of non-volatile buffer components with a volatile buffer.

EDGE
26

Thermo Scientific™ Accucore™ Biphenyl Reversed Phase HPLC Columns

Use this solid core column for fast and reliable separation of critical pairs and isomers.

EDGE
Pore Size 80 Å
Stationary Phase Biphenyl
Temperature 70°C
Phase Reversed Phase
For Use With UHPLC
Endcapped Yes
Surface Area 130 m²/g
Max. Pressure 8700 psi (600 bar)
Particle Size 2.6 μm
Carbon Load 6%
Packing Material Ultrapure Silica
Diameter (Metric) 2.1 mm
pH 2 to 8
Particle Shape Solid Core
Product Line Accucore
USP Type L11
27

Thermo Scientific™ Accucore™ C30 HPLC Columns
GSA_VA

Use this specially designed solid core column for fast, high-resolution separations of hydrophobic, long-chain compounds.

EDGE
Pore Size 150 Å
Particle Size 2.6 μm
Carbon Load 5%
Stationary Phase C30
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Packing Material Ultrapure Silica
pH 2 to 8
Surface Area 80 m²/g
Max. Pressure 14500 psi (1000 bar)
Product Line Accucore
USP Type L62
28

Thermo Scientific™ EASY-Spray™ HPLC Columns

Robust capillary flow HPLC columns for sensitive protein, peptide and mAbs separation using the stand alone or integrated easy to use design.

EDGE
Phase Reversed Phase
29

Thermo Scientific™ ProPac™ WCX-10 HPLC Columns
GSA_VA GREENER_CHOICE

Separate proteins and their variants using these weak cation-exchange columns with exceptionally high resolution.

Pore Size Nonporous
Particle Size 10 μm
Stationary Phase Carboxylate
Temperature 60°C
Phase Ion Exchange
Column Type Ion Exchange
pH 2 to 12
Quantity Each
Product Line ProPac
30

Thermo Scientific™ BioBasic™ 18 HPLC Columns
GSA_VA

Use this 300Å wide-pore silica for the separation of small to medium proteins and other biomolecules.

Pore Size 300 Å
Particle Size 5 μm
Carbon Load 9%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 2 to 9
Surface Area 100 m²/g
USP Type L1